2023 Seed Grant Awardees

PETER FECCI, MD, PHD
Duke University

The CARE-BEAR Proposal

Glioblastoma

This grant was made in memory of our dear friend, Kristen Grossman.

DARYA ALIZADEH, PHD
City of Hope

Advancing IL13Ra2-CAR T cell Therapy against Glioblastoma by Enhancing IFN-Signaling

Glioblastoma

CLAIRE VANPOUILLE-BOX, PHD
Weill Cornell Medicine

Regulation of myeloid cells by fatty acid metabolism in irradiated Glioblastoma 

Glioblastoma

SACHET SHUKLA, PHD
MD Anderson Cancer Center

Identification of non-canonical antigens of development of novel immunotherapies in Glioblastoma

Glioblastoma


2022 Seed Grant Awardees


STAVROULA SOFOU, PHD
Johns Hopkins University

Alpha- particle radiotherapy for glioblastoma

Glioblastoma - Treatment

QIANG LU, PHD
Beckman Research Institute of City of Hope

Engineering inhibitors of the ERKS axis proteins for glioblastoma treatment 

Glioblastoma - Treatment

APARNA BHADURI, PHD
The Regents of the University of California, Los Angeles

Characterizing PTPRZ1 Mechanism in Cancer as a Therapeutic Target

Glioblastoma - Treatment

LIN HUI, PHD
University of California, San Francisco

Developing Multimodal Deep Learning for Outcome Prediction in Glioblastoma Patients after Radiation Therapy

Glioblastoma - Treatment

JANINE LUPO, PHD
University of California, San Francisco

Developing Multimodal Deep Learning for Outcome Prediction in Glioblastoma Patients after Radiation Therapy

Glioblastoma - Treatment


2021 Seed Grant Awardees


CLAIRE VANPOUILLE-BOX, PHD
Weill Cornell Medicine

Targeting CAFs to sensitize irradiated glioblastoma to PD-1 blockade 

Glioblastoma - Treatment

NATHAN DAHL, MD
University of Colorado

PTEFb-dependent transcriptional reorganization in the glioma adaptive response to radiotherapy 

Pediatric - High Grade Gliomas - Treatment

HUGO GUERRERO-CAZARES, MD, PHD 
Mayo Clinic

Targeting the malignant interaction between glioblastoma and the subventricular zone 

Glioblastoma - Science

BETTY KIM, MD, PHD
MD Anderson Cancer Center

Microbial-Inspired STING Activation for Glioblastoma Immunotherapy 

Glioblastoma - Immunotherapeutic treatments


2020 Seed Grant Awardees


MATTHEW WAITKUS, PHD Duke UniversitySynthetic lethal strategies for targeting ATRX deficiency and the Alternative Lengthening of Telomeres in Pediatric High-Grade GliomasPediatric - Gliomas

MATTHEW WAITKUS, PHD
Duke University

Synthetic lethal strategies for targeting ATRX deficiency and the Alternative Lengthening of Telomeres in Pediatric High-Grade Gliomas

Pediatric - Gliomas

MARGARITA GUTOVA, MD City of HopeOvercoming Resistance to CAR T Immunotherapy with CBP/β-catenin Antagonists ICG-001 in BrainTumors: The Road Ahead Towards Metabolic Enhancement of Cancer ImmunotherapyGliomas and Ependymomas - Treatment

MARGARITA GUTOVA, MD
City of Hope

Overcoming Resistance to CAR T Immunotherapy with CBP/β-catenin Antagonists ICG-001 in BrainTumors: The Road Ahead Towards Metabolic Enhancement of Cancer Immunotherapy

Gliomas and Ependymomas - Treatment

JIAN HU, PHD  MD Anderson Cancer CenterEpigenetic Regulation in Pediatric High-Grade GliomasPediatric - Gliomas

JIAN HU, PHD
MD Anderson Cancer Center

Epigenetic Regulation in Pediatric High-Grade Gliomas

Pediatric - Gliomas

LIOR MAYO, PHD Tel Aviv UniversityTargeting Astrocyte Metabolic Reprogramming in GlioblastomaGlioblastoma - Treatment

LIOR MAYO, PHD
Tel Aviv University

Targeting Astrocyte Metabolic Reprogramming in Glioblastoma

Glioblastoma - Treatment


2019 Seed Grant Awardees


ALBERT LAI, MD, PHD University of Los Angeles, CaliforniaParacrine effect of glioma metabolism on immune epigeneticsGlioma - Science

ALBERT LAI, MD, PHD
University of Los Angeles, California

Paracrine effect of glioma metabolism on immune epigenetics

Glioma - Science

VIDYA GOPALAKRISHNAN, PHD  MD Anderson Cancer CenterRepurposing Migraine Treatments for DIPGPediatric - DIPG Treatment

VIDYA GOPALAKRISHNAN, PHD
MD Anderson Cancer Center

Repurposing Migraine Treatments for DIPG

Pediatric - DIPG Treatment

FLORIAN MULLER, PHD MD Anderson Cancer CenterAngiogenesis Inhibited Tumors are Vulnerable to Inhibitor of Oxidative PhosphorylationGlioblastoma - Treatment

FLORIAN MULLER, PHD
MD Anderson Cancer Center

Angiogenesis Inhibited Tumors are Vulnerable to Inhibitor of Oxidative Phosphorylation

Glioblastoma - Treatment

SANTOSH KESARI, MD, PHD John Wayne Cancer InstituteOptimization of OLIG2 inhibition for Glioblastoma treatmentGlioblastoma - Treatment

SANTOSH KESARI, MD, PHD
John Wayne Cancer Institute

Optimization of OLIG2 inhibition for Glioblastoma treatment

Glioblastoma - Treatment


2018 Seed Grant Awardees  


MANISH AGHI, MD, PHD University of California San FranciscoDefining and targeting pro-tumoral effects of cancer-associated fibroblasts in glioblastomaGlioblastoma

MANISH AGHI, MD, PHD
University of California, San Francisco

Defining and targeting pro-tumoral effects of cancer-associated fibroblasts in glioblastoma

Glioblastoma

SANTOSH KESARI, MD, PHD John Wayne Cancer InstituteTargeting metabolic reprogramming in pediatric medulloblastomaPediatric - Medulloblastoma

SANTOSH KESARI, MD, PHD
John Wayne Cancer Institute

Targeting metabolic reprogramming in pediatric medulloblastoma

Pediatric - Medulloblastoma

FREDERICK F. LANG, MD, FACS, FAANS, FAAAS MD Anderson Cancer CenterSuper-selective Intra-arterial Infusion of Human Mesenchymal Stem Cell-based Therapy in a Rabbit Human Glioblastoma ModelGlioblastoma - Treatment

FREDERICK F. LANG, MD, FACS, FAANS, FAAAS
MD Anderson Cancer Center

Super-selective Intra-arterial Infusion of Human Mesenchymal Stem Cell-based Therapy in a Rabbit Human Glioblastoma Model

Glioblastoma - Treatment

ELMAR NURMEMMEDOV, PHD JOHN WAYNE CANCER INSTITUTETargeting inhibition of Beta-catenin in medulloblastomaMedulloblastoma

ELMAR NURMEMMEDOV, PHD
John Wayne Cancer Institute

Targeting inhibition of Beta-catenin in medulloblastoma

Medulloblastoma


2017 Seed Grant Awardees


DAVID A. NATHANSON, PHD University of California, Los AngelesComprehensive characterization of apoptotic blocks in GlioblastomaGlioblastoma

DAVID A. NATHANSON, PHD
University of California, Los Angeles

Comprehensive characterization of apoptotic blocks in Glioblastoma

Glioblastoma

​​ROBERT M. PRINS, PHD University of California, Los AngelesIdentification and cloning of neoantigen-specific T Cells for Glioblastoma immunotherapyGlioblastoma

​​ROBERT M. PRINS, PHD
University of California, Los Angeles

Identification and cloning of neoantigen-specific T Cells for Glioblastoma immunotherapy

Glioblastoma

CHRISTOPHER J. WHEELER, PHD Cedars-Sinai Medical CenterCombination Immunotherapy and Precision Medicine to treat GlioblastomaGlioblastoma

CHRISTOPHER J. WHEELER, PHD
Cedars-Sinai Medical Center

Combination Immunotherapy and Precision Medicine to treat Glioblastoma

Glioblastoma

JUNBAO YANG, MD, PHD​​​​ John Wayne Cancer InstituteSearching the targets on Glioblastoma for immune cells to attack. Specifically, antigen-specific T Cells and antigenic epitope discovery for immunotheraphyGlioblastoma

JUNBAO YANG, MD, PHD​​​
John Wayne Cancer Institute

Searching the targets on Glioblastoma for immune cells to attack. Specifically, antigen-specific T Cells and antigenic epitope discovery for immunotheraphy

Glioblastoma